1.
Indian J Exp Biol
;
1987 Jun; 25(6): 355-9
Article
in English
| IMSEAR
| ID: sea-59943
Subject(s)
Animals , Flow Cytometry , H-2 Antigens/genetics , Haplotypes , Mice , Mice, Inbred Strains , T-Lymphocytes/immunology
2.
Southeast Asian J Trop Med Public Health
;
1984 Dec; 15(4): 518-22
Article
in English
| IMSEAR
| ID: sea-32918
ABSTRACT
The mouse IgE antibody response to S. japonicum antigen (Sj) was found to be under control of a gene(s) linked to the major histocompatibility complex. In some strains but not all among low responders, however, T cell responsiveness to Sj could be demonstrated by the induction of carrier effect as well as by proliferation response. Resistance to reinfection with a large dose of S. japonicum cercariae was demonstrated in most strains examined, except C57BL/6, irrespective of the immune responsiveness. Further studies will be needed to elucidate whether genetically regulated immune responses may affect susceptibility to or pathogenesis of schistosomiasis japonica in the mouse.